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  7. Bauser, Marcus; Giese, Anja; Ellermann, Manuel; Guenther, Judith; Eheim, Ashley; Bunse, Stefanie; Neuhaus, Roland; Weiske, Joerg; Quanz, Maria; Glasauer, Andrea; Nowak-Reppel, Katrin; Bader, Benjamin; Irlbacher, Horst; Meyer, Hanna; Queisser, Nina; Haegebarth, Andrea; Gorjanacz, Matyas; Tresaugues, Lionel; Ginman, Tobias; Rahm, Fredrik; Andersson, Martin; Ericsson, Ulrica; Forsblom, Rickard; Lindstroem, Johan; [...]

    Abstract 689: Identification and optimization of novel chemical matter via a structure-based approach resulting in a probe for MTH1

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    American Association for Cancer Research (AACR), 2018

    Published in: Cancer Research

  8. Rahm, Fredrik; Viklund, Jenny; Trésaugues, Lionel; Ellermann, Manuel; Giese, Anja; Ericsson, Ulrika; Forsblom, Rickard; Ginman, Tobias; Günther, Judith; Hallberg, Kenth; Lindström, Johan; Persson, Lars Boukharta; Silvander, Camilla; Talagas, Antoine; Díaz-Sáez, Laura; Fedorov, Oleg; Huber, Kilian V. M.; Panagakou, Ioanna; Siejka, Paulina; Gorjánácz, Mátyás; Bauser, Marcus; Andersson, Martin

    Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design

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    American Chemical Society (ACS), 2018

    Published in: Journal of Medicinal Chemistry

  9. Ellermann, Manuel; Eheim, Ashley; Rahm, Fredrik; Viklund, Jenny; Guenther, Judith; Andersson, Martin; Ericsson, Ulrika; Forsblom, Rickard; Ginman, Tobias; Lindström, Johan; Silvander, Camilla; Trésaugues, Lionel; Giese, Anja; Bunse, Stefanie; Neuhaus, Roland; Weiske, Jörg; Quanz, Maria; Glasauer, Andrea; Nowak-Reppel, Katrin; Bader, Benjamin; Irlbacher, Horst; Meyer, Hanna; Queisser, Nina; Bauser, Marcus; [...]

    Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target

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    American Chemical Society (ACS), 2017

    Published in: ACS Chemical Biology