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Rieken, Stefan [Author]; Habermehl, Daniel [Author]; Haberer, Thomas [Author]; Jäkel, Oliver [Author]; Debus, Jürgen [Author]; Combs, Stephanie [Author]

Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT) : early treatment results and study concepts

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  • Media type: E-Article
  • Title: Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT) : early treatment results and study concepts
  • Contributor: Rieken, Stefan [VerfasserIn]; Habermehl, Daniel [VerfasserIn]; Haberer, Thomas [VerfasserIn]; Jäkel, Oliver [VerfasserIn]; Debus, Jürgen [VerfasserIn]; Combs, Stephanie [VerfasserIn]
  • imprint: 2012
  • Published in: Radiation oncology ; 7(2012) Artikel-Nummer 41, 7 Seiten
  • Language: English
  • DOI: 10.1186/1748-717X-7-41
  • ISSN: 1748-717X
  • Identifier:
  • Keywords: Glioma ; Meningioma ; Particle therapy ; Toxicity
  • Origination:
  • Footnote: Published: 21 March 2012
  • Description: Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion (18 GyE) vs. a proton boost (10 GyE) in addition to photon radiotherapy (50 Gy), the other one investigating reirradiation with escalating total dose schedules starting at 30 GyE. In atypical meningioma patients (WHO °II), a carbon ion boost of 18 GyE is applied to macroscopic tumor residues following previous photon irradiation with 50 Gy.
  • Access State: Open Access