3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

Medientyp: E-Artikel

Titel: 3D cephalometric analysis using Magnetic Resonance Imaging : validation of accuracy and reproducibility

Beteiligte: Jürchott, Alexander [VerfasserIn]; Saleem, Muhammad Abdullah [VerfasserIn]; Hilgenfeld, Tim [VerfasserIn]; Freudlsperger, Christian [VerfasserIn]; Zingler, Sebastian [VerfasserIn]; Lux, Christopher J. [VerfasserIn]; Bendszus, Martin [VerfasserIn]; Heiland, Sabine [VerfasserIn]

Erschienen: 29 August 2018

Sprache: Englisch

DOI: 10.1038/s41598-018-31384-8

ISSN: 2045-2322

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Beschreibung: The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p 0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.

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