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Medientyp:
Buch
Titel:
Chemogenomics in drug discovery
:
a medicinal chemistry perspective
Enthält:
Target family-directed masterkeyes in chemogenomics
/ Gehard Müller
Literaturangaben
Drug discovery from side effects
/ Hugo Kubinyi
The value of chemical genetics in drug discovery
/ Keith Russell and William F. Michne
Structural aspects of binding site similarity: a 3D upgrade for chemogenomics
/ Andreas Bergner and Judith Günther
The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds
/ Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin
Chemical kinomics
/ Bert M. Klebl, Henrik Daub, and György Kéri
Structural aspects of kinases and their inhibitors
/ Rogier Buijsman
A chemical genomics approach for ion channel modulators
/ Karl-Heinz Baringhaus and Gerhard Hessler
Phosphodiesterase inhibitors: a chemogenomic view
/ Martin Hendrix and Christopher Kallus
Proteochemometrics: a tool for modeling the molecular interaction space
/ Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis
Some principles related to chemogenomics in compound library and template design for GPCRs
/ Thomas R. Webb
Computational filters in lead generation: targeting drug-like chemotypes
/ Wolfgang Guba and Olivier Roche
Navigation in chemical space: ligand-based design of focused compound libraries
/ Gisbert Schneider and Petra Schneider
Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates
/ Marcus A. Koch and Herbert Waldmann
Combinatorial chemistry in the age of chemical genomics
/ Reni Joseph and Prabhat Arya.