• Medientyp: Buch
  • Titel: Pharmacological assays of plant-based natural products
  • Beteiligte: Parimelazhagan, Thangaraj [VerfasserIn]
  • Erschienen: Basel; Heidelberg: Springer, [2016]
  • Erschienen in: Progress in drug research ; 71
  • Umfang: xv, 188 Seiten
  • Sprache: Englisch
  • ISBN: 9783319268101
  • RVK-Notation: VW 5300 : Allgemeines
  • Schlagwörter: Phytochemie > Pflanzeninhaltsstoff > Pharmakologie
  • Entstehung:
  • Anmerkungen: Literaturangaben
  • Beschreibung: "This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant?s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins"--Page 4 of cover

    1. Extraction of plant material -- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays -- 4. In vivo antioxidant assays -- 5. Quantification assays -- 6. Anti-nutritional factors -- 7. Anti-inflammatory activity -- 8. Antipyretic activity -- 9. Inflammation bowel disease -- 10. Anti-arthritic activity -- 11. Evaluation of analgesic potential -- 12. Anti-diarrhoeal activity -- 13. Anti-ulcer activity -- 14. In vitro anti-diabetic activity -- 15. In vivo anti-diabetic activity -- 16. Hepatoprotective property -- 17. Antitumor activity -- 18. In vivo wound healing studies -- 19. Determination of cytotoxicity -- 20. Evaluation of bioavailability -- 21. Molecular identification by DNA barcoding -- 22. Molecular docking of bioactive compounds against BRCA and COX proteins
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