Anmerkungen:
Hinweis: Link zur Erstveröffentlichung URL: https://doi.org/10.3389/fonc.2022.991527
Beschreibung:
Mature T-cell leukemias represent rare, but increasingly recognized diseases of
which, compared to their B-cell counterparts, comparatively little is established on
their pathogenesis, diagnosis, and treatment. These leukemic post-thymic T-cell
neoplasms range from the spectrum of chronic, sometimes debilitating disorders such
as T-large granular lymphocytic leukemia (T-LGLL), and related leukemias such as NKLGLL,
to more aggressive malignancies such as T- prolymphocytic leukemia (T-PLL). In
this series, entitled ‘Pathogenesis, Treatment, and Future Directions for Rare T-cell
Leukemias’ we review the current state of the science of these important T-cell neoplasms
to inform on their treatment, diagnosis, and pathophysiology.