Bainbridge, Emma D;
Hsue, Priscilla Y;
Esensten, Jonathan H;
Lynch, Kara L;
Hendrickson, Carolyn M;
Doernberg, Sarah B;
Fung, Monica;
Chin-Hong, Peter;
Di Germanio, Clara;
Norris, Philip J;
Simmons, Graham;
Glidden, David V;
Luetkemeyer, Anne F
Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019
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Medientyp:
E-Artikel
Titel:
Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019
Beteiligte:
Bainbridge, Emma D;
Hsue, Priscilla Y;
Esensten, Jonathan H;
Lynch, Kara L;
Hendrickson, Carolyn M;
Doernberg, Sarah B;
Fung, Monica;
Chin-Hong, Peter;
Di Germanio, Clara;
Norris, Philip J;
Simmons, Graham;
Glidden, David V;
Luetkemeyer, Anne F
Beschreibung:
<jats:title>Abstract</jats:title>
<jats:p>We characterized the antibody composition of coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) and the immunologic responses of hospitalized COVID-19 patients after receiving CCP or nonimmune fresh frozen plasma. Despite selection of CCP with significantly higher total immunoglobulin G than recipients, neutralizing antibody levels did not differ between donor plasma and CCP recipients.</jats:p>