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Stierman, Bryan; Abrams, Joseph Y.; Godfred-Cato, Shana E.; Oster, Matthew E.; Meng, Lu; Yip, Luke; Patel, Pragna; Balachandran, Neha; Prezzato, Emily; Pierce, Timmy; Hsu, Katherine K.; Burns, Meagan; Peterson Pompa, Xandy; Lauro, Priscilla; Hartley, Amanda; Jones, Cassandra; Gretsch, Stephanie; Reid, Heather; Lim, Sarah; Campbell, Angela P.; Belay, Ermias D.

Racial and Ethnic Disparities in Multisystem Inflammatory Syndrome in Children in the United States, March 2020 to February 2021

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  • Medientyp: E-Artikel
  • Titel: Racial and Ethnic Disparities in Multisystem Inflammatory Syndrome in Children in the United States, March 2020 to February 2021
  • Beteiligte: Stierman, Bryan; Abrams, Joseph Y.; Godfred-Cato, Shana E.; Oster, Matthew E.; Meng, Lu; Yip, Luke; Patel, Pragna; Balachandran, Neha; Prezzato, Emily; Pierce, Timmy; Hsu, Katherine K.; Burns, Meagan; Peterson Pompa, Xandy; Lauro, Priscilla; Hartley, Amanda; Jones, Cassandra; Gretsch, Stephanie; Reid, Heather; Lim, Sarah; Campbell, Angela P.; Belay, Ermias D.
  • Erschienen: Ovid Technologies (Wolters Kluwer Health), 2021
  • Erschienen in: Pediatric Infectious Disease Journal
  • Sprache: Englisch
  • DOI: 10.1097/inf.0000000000003294
  • ISSN: 0891-3668
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:sec> <jats:title>Background:</jats:title> <jats:p>The incidence of multisystem inflammatory syndrome in children (MIS-C) varies by race and ethnicity. This study assessed whether disparities in MIS-C in the United States by race and ethnicity exceed known disparities in coronavirus disease 2019 (COVID-19) incidence.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>We compared the distribution of race and ethnicity among patients with MIS-C (&lt;21 years of age, termed children) with onset March 2020 to February 2021 to that of children with COVID-19 and in the general population. Analysis was restricted to 369 counties with high completeness of race and ethnicity reporting for MIS-C and COVID-19. For each racial and ethnic group, observed numbers of patients with MIS-C were compared with expected numbers (observed/expected ratio) in children with COVID-19 and in the general population within these counties.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>Compared with children in the general population, MIS-C was more frequent among Hispanic (139% of expected) and non-Hispanic Black children (183%) and less frequent among non-Hispanic White (64%) and non-Hispanic Asian children (48%). Compared with children with COVID-19, MIS-C was more frequent in non-Hispanic Black children (207% of expected) and less frequent in non-Hispanic White children (68%); however, frequency was not different among Hispanic (102%) and non-Hispanic Asian (74%) children.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions:</jats:title> <jats:p>Disparities in MIS-C by race and ethnicity exist, even after controlling for COVID-19 disparities and geographic variations. The high proportion of MIS-C among Hispanic children and low proportion among non-Hispanic Asian children align with COVID-19 rates, while the high proportion among non-Hispanic Black children and low proportion among non-Hispanic White children are not explainable by COVID-19 rates.</jats:p> </jats:sec>