Beschreibung:
<jats:title>Abstract</jats:title><jats:p>A mild and versatile method for the synthesis of some novel indole‐1‐carbinols has been developed <jats:italic>via</jats:italic> one‐pot reaction of indoles and paraformaldehyde in the presence of an excess of CaO, MgO, ZnO or TiO<jats:sub>2</jats:sub>. The solvent‐free reaction provided all the indole derivatives in moderate to good yields and short reaction times. Moreover, the effect of some selected indole‐1‐carbinols on cell proliferation of the hepatoma cell line FaO was evaluated.</jats:p>