Beschreibung:
<jats:p>Photolactonization: A Novel Synthetic Entry to Macrolides</jats:p><jats:p><jats:italic>o</jats:italic>‐Quinol acetates, hydroxyalkylated at C(6), are easily accessible from simple phenols by <jats:italic>Wessely</jats:italic> acetoxylation (preferentially catalyzed by BF<jats:sub>3</jats:sub>). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones. Subtle conditions have been elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides has been elucidated.</jats:p>