• Medientyp: E-Artikel
  • Titel: Intraocular Langerhans cell histiocytosis in a neonate resulting in bilateral loss of vision
  • Beteiligte: Boztug, Kaan; Frimpong‐Ansah, Kwabena; Nanduri, Vasanta Rao; Lawson, Joanna; Russell‐Eggitt, Isabelle; Brock, Penelope
  • Erschienen: Wiley, 2006
  • Erschienen in: Pediatric Blood & Cancer
  • Sprache: Englisch
  • DOI: 10.1002/pbc.20714
  • ISSN: 1545-5009; 1545-5017
  • Schlagwörter: Oncology ; Hematology ; Pediatrics, Perinatology and Child Health
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Intraocular involvement in Langerhans cell histiocytosis (LCH) is rare. We describe the case of a neonate with congenital disseminated LCH involving skin, liver, spleen, and intraocular structures including uvea and retina. Early and aggressive treatment according to the LCH‐II treatment protocol was administered and resulted in remission of the disease. However, despite close follow‐up and additional local treatment, involvement of intraocular structures resulted in severe long‐term ophthalmological sequelae including complete bilateral loss of vision. Pediatr Blood Cancer 2006; 47:633–635. © 2006 Wiley‐Liss, Inc.</jats:p>