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Ranoa, Diana Rose E.; Holland, Robin L.; Alnaji, Fadi G.; Green, Kelsie J.; Wang, Leyi; Fredrickson, Richard L.; Wang, Tong; Wong, George N.; Uelmen, Johnny; Maslov, Sergei; Weiner, Zachary J.; Tkachenko, Alexei V.; Zhang, Hantao; Liu, Zhiru; Ibrahim, Ahmed; Patel, Sanjay J.; Paul, John M.; Vance, Nickolas P.; Gulick, Joseph G.; Satheesan, Sandeep Puthanveetil; Galvan, Isaac J.; Miller, Andrew; Grohens, Joseph; Nelson, Todd J.; [...]

Mitigation of SARS-CoV-2 transmission at a large public university

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  • Medientyp: E-Artikel
  • Titel: Mitigation of SARS-CoV-2 transmission at a large public university
  • Beteiligte: Ranoa, Diana Rose E.; Holland, Robin L.; Alnaji, Fadi G.; Green, Kelsie J.; Wang, Leyi; Fredrickson, Richard L.; Wang, Tong; Wong, George N.; Uelmen, Johnny; Maslov, Sergei; Weiner, Zachary J.; Tkachenko, Alexei V.; Zhang, Hantao; Liu, Zhiru; Ibrahim, Ahmed; Patel, Sanjay J.; Paul, John M.; Vance, Nickolas P.; Gulick, Joseph G.; Satheesan, Sandeep Puthanveetil; Galvan, Isaac J.; Miller, Andrew; Grohens, Joseph; Nelson, Todd J.; [...]
  • Erschienen: Springer Science and Business Media LLC, 2022
  • Erschienen in: Nature Communications
  • Sprache: Englisch
  • DOI: 10.1038/s41467-022-30833-3
  • ISSN: 2041-1723
  • Schlagwörter: General Physics and Astronomy ; General Biochemistry, Genetics and Molecular Biology ; General Chemistry ; Multidisciplinary
  • Entstehung:
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>In Fall 2020, universities saw extensive transmission of SARS-CoV-2 among their populations, threatening health of the university and surrounding communities, and viability of in-person instruction. Here we report a case study at the University of Illinois at Urbana-Champaign, where a multimodal “SHIELD: Target, Test, and Tell” program, with other non-pharmaceutical interventions, was employed to keep classrooms and laboratories open. The program included epidemiological modeling and surveillance, fast/frequent testing using a novel low-cost and scalable saliva-based RT-qPCR assay for SARS-CoV-2 that bypasses RNA extraction, called covidSHIELD, and digital tools for communication and compliance. In Fall 2020, we performed &gt;1,000,000 covidSHIELD tests, positivity rates remained low, we had zero COVID-19-related hospitalizations or deaths amongst our university community, and mortality in the surrounding Champaign County was reduced more than 4-fold relative to expected. This case study shows that fast/frequent testing and other interventions mitigated transmission of SARS-CoV-2 at a large public university.</jats:p>
  • Zugangsstatus: Freier Zugang