The utility of the Edmonton Obesity Staging System for the prediction of COVID-19 outcomes: a multi-centre study

Medientyp: E-Artikel
Titel: The utility of the Edmonton Obesity Staging System for the prediction of COVID-19 outcomes: a multi-centre study
Beteiligte: Rodríguez-Flores, Marcela; Goicochea-Turcott, Eduardo W.; Mancillas-Adame, Leonardo; Garibay-Nieto, Nayely; López-Cervantes, Malaquías; Rojas-Russell, Mario E.; Castro-Porras, Lilia V.; Gutiérrez-León, Eduardo; Campos-Calderón, Luis F.; Pedraza-Escudero, Karen; Aguilar-Cuarto, Karina; Villanueva-Ortega, Eréndira; Hernández-Ruíz, Joselin; Guerrero-Avendaño, Guadalupe; Monzalvo-Reyes, Sheyla M.; García-Rascón, Rafael; Gil-Velázquez, Israel N.; Cortés-Hernández, Dora E.; Granados-Shiroma, Marcela; Alvarez-Rodríguez, Brenda G.; Cabello-Garza, Martha L.; González-Contreras, Zaira L.; Picazo-Palencia, Esteban; Cerda-Arteaga, Juana M.; [...]
Erschienen: Springer Science and Business Media LLC, 2022
Erschienen in: International Journal of Obesity
Sprache: Englisch
DOI: 10.1038/s41366-021-01017-8
ISSN: 0307-0565; 1476-5497
Schlagwörter: Nutrition and Dietetics ; Endocrinology, Diabetes and Metabolism ; Medicine (miscellaneous)
Entstehung:
Anmerkungen:
Beschreibung: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Patients with obesity have an increased risk for adverse COVID-19 outcomes. Body mass index (BMI) does not acknowledge the health burden associated this disease. The performance of the Edmonton Obesity Staging System (EOSS), a clinical classification tool that assesses obesity-related comorbidity, is compared with BMI, with respect to adverse COVID-19 outcomes.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>1071 patients were evaluated in 11 COVID-19 hospitals in Mexico. Patients were classified into EOSS stages. Adjusted risk factors for COVID-19 outcomes were calculated and survival analysis for mechanical ventilation and death was carried out according to EOSS stage and BMI category.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The risk for intubation was higher in patients with EOSS stages 2 and 4 (HR 1.42, 95% CI 1.02–1.97 and 2.78, 95% CI 1.83–4.24), and in patients with BMI classes II and III (HR 1.71, 95% CI 1.06–2.74, and 2.62, 95% CI 1.65–4.17). Mortality rates were significantly lower in patients with EOSS stages 0 and 1 (HR 0.62, 95% CI 0.42–0.92) and higher in patients with BMI class III (HR 1.58, 95% CI 1.03–2.42). In patients with a BMI ≥ 25 kg/m<jats:sup>2</jats:sup>, the risk for intubation increased with progressive EOSS stages. Only individuals in BMI class III showed an increased risk for intubation (HR 2.24, 95% CI 1.50–3.34). Mortality risk was increased in EOSS stages 2 and 4 compared to EOSS 0 and 1, and in patients with BMI class II and III, compared to patients with overweight.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>EOSS was associated with adverse COVID-19 outcomes, and it distinguished risks beyond BMI. Patients with overweight and obesity in EOSS stages 0 and 1 had a lower risk than patients with normal weight. BMI does not adequately reflect adipose tissue-associated disease, it is not ideal for guiding chronic-disease management.</jats:p> </jats:sec>

Nur in Feld suchen:

Zuletzt gesuchte Begriffe: