Beschreibung:
<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background/Objectives</jats:title>
<jats:p>To evaluate anthropometric measures for the prediction of whole-abdominal adipose tissue volumes <jats:italic>V</jats:italic><jats:sub>XAT</jats:sub> (subcutaneous <jats:italic>V</jats:italic><jats:sub>SAT</jats:sub>, visceral <jats:italic>V</jats:italic><jats:sub>VAT</jats:sub> and total <jats:italic>V</jats:italic><jats:sub>TAT</jats:sub>) in patients with obesity.</jats:p>
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<jats:title>Subjects/Methods</jats:title>
<jats:p>A total of 181 patients (108 women) with overweight or obesity were analyzed retrospectively. MRI data (1.5 T) were available from independent clinical trials at a single institution (Integrated Research and Treatment Center of Obesity, University of Leipzig). A custom-made software was used for automated tissue segmentation. Anthropometric parameters (<jats:italic>AP</jats:italic>) were circumferences of the waist (WC) and hip (HC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and the (hypothetical) hip-to-height ratio (HHtR). Agreement was evaluated by standard deviations <jats:italic>s</jats:italic><jats:sub>d%</jats:sub> of percent differences between estimated volumes (using results of linear <jats:italic>AP</jats:italic>–<jats:italic>V</jats:italic><jats:sub>XAT</jats:sub> regression) and measured ones as well as Pearson’s correlation coefficient <jats:italic>r</jats:italic>.</jats:p>
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<jats:title>Results</jats:title>
<jats:p>For SAT volume estimation, the smallest <jats:italic>s</jats:italic><jats:sub>d%</jats:sub> for all patients was seen for HC (25.1%) closely followed by HHtR (25.2%). Sex-specific results for females (17.5% for BMI and 17.2% for HC) and males (20.7% for WC) agreed better. VAT volumes could not be estimated reliably by any of the anthropometric measures considered here. TAT volumes in a mixed population could be best estimated by BMI closely followed by WC (roughly 17.5%). A sex-specific consideration reduced the deviations to around 16% for females (BMI and WC) and below 14% for males (WC).</jats:p>
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<jats:title>Conclusions</jats:title>
<jats:p>We suggest the use of sex-specific parameters–BMI or HC for females and WC for males–for the estimation of abdominal SAT and TAT volumes in patients with overweight or obesity.</jats:p>
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