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Medientyp:
E-Artikel
Titel:
In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
Beteiligte:
Banzhaf, Christina Alette;
Themstrup, Lotte;
Ring, Hans Christian;
Welzel, Julia;
Mogensen, Mette;
Jemec, Gregor Borut Ernst
Erschienen:
S. Karger AG, 2013
Erschienen in:Case Reports in Dermatology
Sprache:
Englisch
DOI:
10.1159/000352066
ISSN:
1662-6567
Entstehung:
Anmerkungen:
Beschreibung:
<jats:p><b><i>Background:</i></b><i>Sarcoptes scabiei</i> can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. <b><i>Methods:</i></b> Five patients from the Departments of Dermatology, Augsburg, Germany, and Roskilde, Denmark, were OCT scanned (VivoSight®; Michelson Diagnostics Ltd., UK). Mites were identified by epiluminescence and light microscopy to confirm the diagnosis. <b><i>Results:</i></b> OCT identified <i>S. scabiei</i> mites in all patients in vivo. Mites and burrows were visualized, and some detail on burrow content was provided. <b><i>Conclusion:</i></b> OCT can visualize <i>S. scabiei</i> mites in vivo, suggesting that it may be used to study the biology of the mites in vivo and provide early assessment of scabicide therapy. OCT is able to visualize structures in the skin with an 8-µm resolution. Therefore, this technology could potentially allow rapid, non-invasive, in vivo diagnosis and analysis of infestations.</jats:p>