• Medientyp: E-Artikel
  • Titel: Increased Levels of Soluble Fas Ligand in Serum in Plasmodium falciparum Malaria
  • Beteiligte: Kern, Peter; Dietrich, Manfred; Hemmer, Christoph; Wellinghausen, Nele
  • Erschienen: American Society for Microbiology, 2000
  • Erschienen in: Infection and Immunity
  • Sprache: Englisch
  • DOI: 10.1128/iai.68.5.3061-3063.2000
  • ISSN: 0019-9567; 1098-5522
  • Schlagwörter: Infectious Diseases ; Immunology ; Microbiology ; Parasitology
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  • Beschreibung: <jats:title>ABSTRACT</jats:title> <jats:p> Levels of soluble Fas ligand (sFasL) in serum were elevated in patients with <jats:italic>Plasmodium falciparum</jats:italic> malaria and showed a significant decline during disease course. sFasL levels that were elevated before antimalarial treatment began correlated significantly with depressed total lymphocyte and T-cell counts. These data suggest that Fas-induced apoptosis might play a role in malaria-associated lymphopenia. </jats:p>
  • Zugangsstatus: Freier Zugang