• Medientyp: E-Artikel
  • Titel: More Patients with Optimal Glycemic Control after Participation in a CSII-Specific Education Program (INPUT)—Results from a Randomized Controlled Study
  • Beteiligte: KULZER, BERNHARD; EHRMANN, DOMINIC; SCHIPFER, MELANIE; LIPPMANN-GROB, BERNHARD; HAAK, THOMAS; HERMANNS, NORBERT
  • Erschienen: American Diabetes Association, 2018
  • Erschienen in: Diabetes
  • Sprache: Englisch
  • DOI: 10.2337/db18-671-p
  • ISSN: 0012-1797; 1939-327X
  • Schlagwörter: Endocrinology, Diabetes and Metabolism ; Internal Medicine
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  • Anmerkungen:
  • Beschreibung: <jats:p>Despite the technological advances of CSII-therapy, many patients with CSII-therapy do not achieve optimal glycemic control. We developed an education program for CSII-therapy (INPUT) and evaluated its efficacy in a randomized controlled trial with a six-month follow-up. INPUT addresses the specific knowledge and skills to effectively handle CSII-therapy as well as possible psychological barriers. We analyzed whether participation in the INPUT program increased the number of patients with optimal glycemic control (HbA1c &amp;lt; 7.5%). 254 patients with CSII-therapy were randomized to either receive the INPUT education program or treatment-as-usual and were assessed at follow-up. All patients were already performing CSII-therapy for 8.7 ± 6.8 years, with a mean diabetes duration of 23.1 ± 12.6 years. HbA1c at baseline was 8.3 ± 0.9%. Optimal glycemic control at baseline was achieved by 13% in the INPUT group and 20% in the control Group. Logistic regression with group as independent factor controlling for optimal glycemic control at baseline was performed. Dependent variable was optimal glycemic control at the six-month follow-up. Group was a significant predictor with INPUT patients having a 2-fold higher chance to achieve optimal glycemic control (OR = 1.98; 95% CI 1.04-3.78; p = 0.037) compared to patients in the control group. At follow-up, 27% of the INPUT group had achieved optimal glycemic control while only 18 % in the control group. In this study, patients performed CSII-therapy for almost 10 years without achieving optimal glycemic control. After participation in INPUT, patient more often achieved optimal glycemic control compared to a treatment-as-usual control group. Thus, the INPUT education program was effective in improving glycemic control in patients with long-standing diabetes. Considering the higher costs of CSII-therapy, this beneficial effect of the education program has health-economic implications.</jats:p> <jats:sec> <jats:title>Disclosure</jats:title> <jats:p>B. Kulzer: Research Support; Self; Berlin-Chemie AG. Speaker's Bureau; Self; Berlin-Chemie AG, Novo Nordisk Inc.. Advisory Panel; Self; Roche Diabetes Care Health and Digital Solutions. Speaker's Bureau; Self; Roche Diabetes Care Health and Digital Solutions. Research Support; Self; Abbott. Speaker's Bureau; Self; Abbott, Eli Lilly and Company. Advisory Panel; Self; Novo Nordisk Inc., Medtronic, Ascensia Diabetes Care. Speaker's Bureau; Self; Ascensia Diabetes Care. D. Ehrmann: Speaker's Bureau; Self; Berlin-Chemie AG. M. Schipfer: Speaker's Bureau; Self; Medtronic, Lilly Diabetes Germany. B. Lippmann-Grob: Speaker's Bureau; Self; Berlin-Chemie AG. Advisory Panel; Self; Novo Nordisk Inc., Eli Lilly and Company. T. Haak: Speaker's Bureau; Self; Abbott. Advisory Panel; Self; Roche Diabetes Care Health and Digital Solutions, Sanofi, Eli Lilly and Company. Speaker's Bureau; Self; Eli Lilly and Company, AstraZeneca. N. Hermanns: Speaker's Bureau; Self; Berlin-Chemie AG. Advisory Panel; Self; Abbott. Research Support; Self; Abbott. Speaker's Bureau; Self; Abbott. Research Support; Self; Berlin-Chemie AG. Advisory Panel; Self; Eli Lilly and Company. Speaker's Bureau; Self; Eli Lilly and Company. Advisory Panel; Self; Roche Diabetes Care Health and Digital Solutions. Research Support; Self; Ypsomed AG, Dexcom, Inc.. Speaker's Bureau; Self; Novo Nordisk Inc..</jats:p> </jats:sec>
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