• Medientyp: E-Artikel
  • Titel: Examining the Acute Glycemic Effects of Different Types of Structured Exercise Sessions in Type 1 Diabetes in a Real-World Setting: The Type 1 Diabetes and Exercise Initiative (T1DEXI)
  • Beteiligte: Riddell, Michael C.; Li, Zoey; Gal, Robin L.; Calhoun, Peter; Jacobs, Peter G.; Clements, Mark A.; Martin, Corby K.; Doyle III, Francis J.; Patton, Susana R.; Castle, Jessica R.; Gillingham, Melanie B.; Beck, Roy W.; Rickels, Michael R.; Riddell, Michael C.; Rickels, Michael R.; Beck, Roy W.; Castle, Jessica R.; Calhoun, Peter; Clements, Mark A.; Doyle, Francis J.; Gal, Robin L.; Gillingham, Melanie B.; Jacobs, Peter G.; Li, Zoey; [...]
  • Erschienen: American Diabetes Association, 2023
  • Erschienen in: Diabetes Care
  • Sprache: Englisch
  • DOI: 10.2337/dc22-1721
  • ISSN: 0149-5992; 1935-5548
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:sec><jats:title>OBJECTIVE</jats:title><jats:p>Maintenance of glycemic control during and after exercise remains a major challenge for individuals with type 1 diabetes. Glycemic responses to exercise may differ by exercise type (aerobic, interval, or resistance), and the effect of activity type on glycemic control after exercise remains unclear.</jats:p></jats:sec><jats:sec><jats:title>RESEARCH DESIGN AND METHODS</jats:title><jats:p>The Type 1 Diabetes Exercise Initiative (T1DEXI) was a real-world study of at-home exercise. Adult participants were randomly assigned to complete six structured aerobic, interval, or resistance exercise sessions over 4 weeks. Participants self-reported study and nonstudy exercise, food intake, and insulin dosing (multiple daily injection [MDI] users) using a custom smart phone application and provided pump (pump users), heart rate, and continuous glucose monitoring data.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>A total of 497 adults with type 1 diabetes (mean age ± SD 37 ± 14 years; mean HbA1c ± SD 6.6 ± 0.8% [49 ± 8.7 mmol/mol]) assigned to structured aerobic (n = 162), interval (n = 165), or resistance (n = 170) exercise were analyzed. The mean (± SD) change in glucose during assigned exercise was −18 ± 39, −14 ± 32, and −9 ± 36 mg/dL for aerobic, interval, and resistance, respectively (P &amp;lt; 0.001), with similar results for closed-loop, standard pump, and MDI users. Time in range 70–180 mg/dL (3.9–10.0 mmol/L) was higher during the 24 h after study exercise when compared with days without exercise (mean ± SD 76 ± 20% vs. 70 ± 23%; P &amp;lt; 0.001).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>Adults with type 1 diabetes experienced the largest drop in glucose level with aerobic exercise, followed by interval and resistance exercise, regardless of insulin delivery modality. Even in adults with well-controlled type 1 diabetes, days with structured exercise sessions contributed to clinically meaningful improvement in glucose time in range but may have slightly increased time below range.</jats:p></jats:sec>
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