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Theuring, Stefanie; Thielecke, Marlene; van Loon, Welmoed; Hommes, Franziska; Hülso, Claudia; von der Haar, Annkathrin; Körner, Jennifer; Schmidt, Michael; Böhringer, Falko; Mall, Marcus A; Rosen, Alexander; von Kalle, Christof; Kirchberger, Valerie; Kurth, Tobias; Seybold, Joachim; Mockenhaupt, Frank P

SARS-CoV-2 infection and transmission in school settings during the second COVID-19 wave: a cross-sectional study, Berlin, Germany, November 2020

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  • Medientyp: E-Artikel
  • Titel: SARS-CoV-2 infection and transmission in school settings during the second COVID-19 wave: a cross-sectional study, Berlin, Germany, November 2020
  • Beteiligte: Theuring, Stefanie; Thielecke, Marlene; van Loon, Welmoed; Hommes, Franziska; Hülso, Claudia; von der Haar, Annkathrin; Körner, Jennifer; Schmidt, Michael; Böhringer, Falko; Mall, Marcus A; Rosen, Alexander; von Kalle, Christof; Kirchberger, Valerie; Kurth, Tobias; Seybold, Joachim; Mockenhaupt, Frank P
  • Erschienen: European Centre for Disease Control and Prevention (ECDC), 2021
  • Erschienen in: Eurosurveillance
  • Sprache: Englisch
  • DOI: 10.2807/1560-7917.es.2021.26.34.2100184
  • ISSN: 1560-7917
  • Schlagwörter: Virology ; Public Health, Environmental and Occupational Health ; Epidemiology
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:sec> <jats:title>Background</jats:title> <jats:p>School attendance during the COVID-19 pandemic is intensely debated.</jats:p> </jats:sec> <jats:sec> <jats:title>Aim</jats:title> <jats:p>In November 2020, we assessed SARS-CoV-2 infections and seroreactivity in 24 randomly selected school classes and connected households in Berlin, Germany.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>We collected oro-nasopharyngeal swabs and blood samples, examining SARS-CoV-2 infection and IgG antibodies by RT-PCR and ELISA. Household members self-swabbed. We assessed individual and institutional prevention measures. Classes with SARS-CoV-2 infection and connected households were retested after 1 week.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>We examined 1,119 participants, including 177 primary and 175 secondary school students, 142 staff and 625 household members. SARS-CoV-2 infection occurred in eight classes, affecting each 1–2 individuals. Infection prevalence was 2.7% (95% confidence interval (CI): 1.2–5.0; 9/338), 1.4% (95% CI: 0.2–5.1; 2/140), and 2.3% (95% CI: 1.3–3.8; 14/611) among students, staff and household members. Six of nine infected students were asymptomatic at testing. We detected IgG antibodies in 2.0% (95%CI: 0.8–4.1; 7/347), 1.4% (95% CI: 0.2–5.0; 2/141) and 1.4% (95% CI: 0.6–2.7; 8/576). Prevalence increased with inconsistent facemask-use in school, walking to school, and case-contacts outside school. For three of nine households with infection(s), origin in school seemed possible. After 1 week, no school-related secondary infections appeared in affected classes; the attack rate in connected households was 1.1%.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>School attendance under rigorously implemented preventive measures seems reasonable. Balancing risks and benefits of school closures need to consider possible spill-over infection into households. Deeper insight is required into the infection risks due to being a schoolchild vs attending school.</jats:p> </jats:sec>
  • Zugangsstatus: Freier Zugang