• Media type: E-Article
  • Title: Comparative study of characteristics and disease management between subjects with frequent and occasional gastro‐oesophageal reflux symptoms
  • Contributor: BRETAGNE, J. F.; HONNORAT, C.; RICHARD‐MOLARD, B.; CAEKAERT, A.; BARTHÉLEMY, P.
  • imprint: Wiley, 2006
  • Published in: Alimentary Pharmacology & Therapeutics
  • Language: English
  • DOI: 10.1111/j.1365-2036.2006.02811.x
  • ISSN: 0269-2813; 1365-2036
  • Keywords: Pharmacology (medical) ; Gastroenterology ; Hepatology
  • Origination:
  • Footnote:
  • Description: <jats:title>Summary</jats:title><jats:p><jats:bold>Background </jats:bold> Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro‐oesophageal reflux symptoms.</jats:p><jats:p><jats:bold>Aim </jats:bold> To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro‐oesophageal reflux symptoms.</jats:p><jats:p><jats:bold>Methods </jats:bold> Population‐based postal survey carried out in France in 2003 among a representative sample of 8000 subjects.</jats:p><jats:p><jats:bold>Results </jats:bold> The prevalence of frequent and occasional gastro‐oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro‐oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton‐pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro‐oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton‐pump inhibitors.</jats:p><jats:p><jats:bold>Conclusions </jats:bold> This survey suggests that subjects complaining of frequent or occasional gastro‐oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health‐related quality of life and sought health care.</jats:p>
  • Access State: Open Access