• Media type: E-Article
  • Title: Obtaining and Characterization of a Polyurethane Carrier Used for Eugenol as a Possible Remedy in Oral Therapies
  • Contributor: Popa, Zoran; Rusu, Laura Cristina; Susan, Razvan; Pinzaru, Iulia; Ardelean, Elena; Borcan, Florin; Voicu, Mirela; Sas, Ioana Tuta; Lazureanu, Ramona Amina Popovici Voichita
  • imprint: Revista de Chimie SRL, 2018
  • Published in: Materiale Plastice
  • Language: English
  • DOI: 10.37358/mp.18.1.4953
  • ISSN: 0025-5289; 2668-8220
  • Keywords: Materials Chemistry ; Polymers and Plastics ; Mechanics of Materials ; General Chemistry
  • Origination:
  • Footnote:
  • Description: <jats:p> The cloves are antiseptic, antiparasitic, antibacterial, antifungal, antiviral, anesthetic, analgesic, anti-inflammatory, tonic, carminative, anti-ulcer, antithrombotic, antioxidant and anti-cancerous. They contain eugenol, tannins and flavonoids that also help to strengthen the vein wall. This paper presents the obtaining and the characterization of a polyurethane drug delivery system which can be used for the transmembrane transport of eugenol in oral therapies. The products were analyzed by pH and solubility measurements, thermal decomposition and zetasizer tests and they were applied on mice skin to evaluate their harmfulness. The results suggest that were obtained neutral pH structures with low solubility and a good thermal stability, with sizes between 241 and 289 nm and no toxicity effect was found in the case of studied samples. </jats:p>
  • Access State: Open Access