Julious, Steven A.
[VerfasserIn];
Tan, Say Beng
[VerfasserIn]
;
Julious, Steven
[Sonstige Person, Familie und Körperschaft];
Machin, David
[Sonstige Person, Familie und Körperschaft]
An introduction to statistics in early phase trials
Anmerkungen:
Includes bibliographical references and index
Beschreibung:
Early phase trials -- Introduction to pharmacokinetics -- Sample size calculations for clinical trials -- Crossover trial basics -- Multiperiod crossover trials -- First time into man -- Bayesian and frequentist methods -- First-time-into-new-population studies -- Bioequivalence studies -- Other phase I trials -- Phase II trials : general issues -- Dose/response studies -- Phase II trials with toxic therapies -- Interpreting and applying early phase trial results -- Go/no-go criteria