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Mertens, Andrew; Benjamin-Chung, Jade; Colford, John M.; Hubbard, Alan E.; van der Laan, Mark J.; Coyle, Jeremy; Sofrygin, Oleg; Cai, Wilson; Jilek, Wendy; Rosete, Sonali; Nguyen, Anna; Pokpongkiat, Nolan N.; Djajadi, Stephanie; Seth, Anmol; Jung, Esther; Chung, Esther O.; Malenica, Ivana; Hejazi, Nima; Li, Haodong; Hafen, Ryan; Subramoney, Vishak; Häggström, Jonas; Norman, Thea; Christian, Parul; [...]

Child wasting and concurrent stunting in low- and middle-income countries

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  • Medientyp: E-Artikel
  • Titel: Child wasting and concurrent stunting in low- and middle-income countries
  • Beteiligte: Mertens, Andrew; Benjamin-Chung, Jade; Colford, John M.; Hubbard, Alan E.; van der Laan, Mark J.; Coyle, Jeremy; Sofrygin, Oleg; Cai, Wilson; Jilek, Wendy; Rosete, Sonali; Nguyen, Anna; Pokpongkiat, Nolan N.; Djajadi, Stephanie; Seth, Anmol; Jung, Esther; Chung, Esther O.; Malenica, Ivana; Hejazi, Nima; Li, Haodong; Hafen, Ryan; Subramoney, Vishak; Häggström, Jonas; Norman, Thea; Christian, Parul; [...]
  • Erschienen: Springer Science and Business Media LLC, 2023
  • Erschienen in: Nature
  • Sprache: Englisch
  • DOI: 10.1038/s41586-023-06480-z
  • ISSN: 0028-0836; 1476-4687
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Sustainable Development Goal 2.2—to end malnutrition by 2030—includes the elimination of child wasting, defined as a weight-for-length <jats:italic>z</jats:italic>-score that is more than two standard deviations below the median of the World Health Organization standards for child growth<jats:sup>1</jats:sup>. Prevailing methods to measure wasting rely on cross-sectional surveys that cannot measure onset, recovery and persistence—key features that inform preventive interventions and estimates of disease burden. Here we analyse 21 longitudinal cohorts and show that wasting is a highly dynamic process of onset and recovery, with incidence peaking between birth and 3 months. Many more children experience an episode of wasting at some point during their first 24 months than prevalent cases at a single point in time suggest. For example, at the age of 24 months, 5.6% of children were wasted, but by the same age (24 months), 29.2% of children had experienced at least one wasting episode and 10.0% had experienced two or more episodes. Children who were wasted before the age of 6 months had a faster recovery and shorter episodes than did children who were wasted at older ages; however, early wasting increased the risk of later growth faltering, including concurrent wasting and stunting (low length-for-age <jats:italic>z</jats:italic>-score), and thus increased the risk of mortality. In diverse populations with high seasonal rainfall, the population average weight-for-length <jats:italic>z</jats:italic>-score varied substantially (more than 0.5 <jats:italic>z</jats:italic> in some cohorts), with the lowest mean <jats:italic>z</jats:italic>-scores occurring during the rainiest months; this indicates that seasonally targeted interventions could be considered. Our results show the importance of establishing interventions to prevent wasting from birth to the age of 6 months, probably through improved maternal nutrition, to complement current programmes that focus on children aged 6–59 months.</jats:p>