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Medientyp:
E-Artikel
Titel:
Natural products from microbes associated with insects
Beteiligte:
Beemelmanns, Christine;
Guo, Huijuan;
Rischer, Maja;
Poulsen, Michael
Erschienen:
Beilstein Institut, 2016
Erschienen in:Beilstein Journal of Organic Chemistry
Sprache:
Englisch
DOI:
10.3762/bjoc.12.34
ISSN:
1860-5397
Entstehung:
Anmerkungen:
Beschreibung:
<jats:p>Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial–host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.</jats:p>